Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hupSHydrogenase small subunit. (290 aa)    
Predicted Functional Partners:
hupL
Hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 0.999
CBO1332
Putative oxidoreductase, electron transfer subunit.
  
 
 0.935
hupD
Putative hydrogenase maturation protein.
 
  
 0.918
cooS
Putative oxidoreductase, acetyl-CoA synthase subunit.
    
 0.907
cooS-2
Putative carbon monoxide dehydrogenase beta subunit.
    
 0.907
hypF
Hydrogenase maturation protein.
 
 
 
 0.899
hypD
Hydrogenase isoenzymes formation protein.
 
  
 0.889
hypE
Hydrogenase isoenzymes formation protein.
 
   
 0.874
hypB-2
Similar to the C-terminal region of Escherichia coli, and Escherichia coli O6 hydrogenase isoenzymes nickel incorporation protein HypB or b2727 or c3287 SWALL:HYPB_ECOLI (SWALL:P24190) (290 aa) fasta scores: E(): 3e-25, 42.99 38d in 207 aa. Similar to the full length Thermoanaerobacter tengcongensis Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase TTE0130 SWALL:Q8RDB1 (EMBL:AE012986) (218 aa) fasta scores: E(): 5.2e-25,44.66 38d in 206 aa.
 
  
 0.783
hypB
Hydrogenase nickel incorporation protein; Similar to Escherichia coli, and Escherichia coli O6 hydrogenase isoenzymes nickel incorporation protein HypB or b2727 or c3287 SWALL:HYPB_ECOLI (SWALL:P24190) (290 aa) fasta scores: E(): 3e-28, 40.74 38d in 216 aa.
 
  
 0.709
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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