Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBO1871DNA integration/recombination protein. (264 aa)    
Predicted Functional Partners:
spo0A
Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
       0.553
CBO0171
Putative phosphoribosyl transferase; Similar to Haemophilus influenzae competence protein F ComF or hi0434 SWALL:COMF_HAEIN (SWALL:P31773) (229 aa) fasta scores: E(): 4.7e-05, 25.83 38d in 209 aa,and to Clostridium acetobutylicum predicted amidophosphoribosyltransferase, ComC b.suntilis ortholog cac2852 SWALL:Q97F89 (EMBL:AE007783) (226 aa) fasta scores: E(): 6.3e-31, 46.63 38d in 208 aa.
   
    0.524
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
   
    0.493
CBO1870
Hypothetical protein; No significant database matches.
       0.489
hsdM
Type I restriction enzyme M subunit.
 
   
 0.466
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
   
  
 0.455
hsdS
Type I restriction enzyme S subunit.
 
  
 0.413
hsdR
Type I restriction enzyme R subunit.
 
   
 0.401
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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