Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
spoIIIAGStage III sporulation protein AG. (198 aa)    
Predicted Functional Partners:
CBO1888
Putative exported protein.
 
  
 0.993
spoIIIAF
Stage III sporulation protein AF.
 
  
 0.992
spoIIIAA
Stage III sporulation protein AA.
 
  
 0.986
spoIIIAE
Stage III sporulation protein AE.
 
  
 0.977
spoIIIAB
Stage III sporulation protein AB.
 
  
 0.974
spoIIIAD
Stage III sporulation protein AD.
 
  
 0.951
spoIIIAC
Stage III sporulation protein AC.
 
  
 0.923
spoIIID
Similar to Bacillus subtilis stage III sporulation protein D SpoIIID or bsu36420 SWALL:SP3D_BACSU (SWALL:P15281) (93 aa) fasta scores: E(): 1.1e-16, 62.65 id in 83 aa, and to Clostridium acetobutylicum stage iii sporulation protein D SpoIIID cac2859 SWALL:Q97F82 (EMBL:AE007783) (84 aa) fasta scores: E(): 9e-24, 89.28 id in 84 aa.
  
  
 0.899
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.884
spo0A
Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
 
   
 0.849
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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