STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO1963Putative aminotransferase. (389 aa)    
Predicted Functional Partners:
metC
Cystathionine beta-lyase.
 
 
 0.936
metH
Putative methionine synthase.
     
 0.930
cysD
O-acetylhomoserine sulfhydrylase.
    
 0.917
cysK1
Cysteine synthase 1; Also similar to CBO0205 (53.5 38d); Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.914
cysK2
Cysteine synthase 2; Also similar to CBO0205 (53.5 38d); Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.914
aspC-2
Aspartate aminotransferase.
 
  
0.911
cysK
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.910
CBO1400
Putative aminotransferase.
  
  
 
0.906
luxS
S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
 0.904
CBO1014
Putative aromatic amino acid aminotransferase.
    
 0.903
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (16%) [HD]