STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruAPTS system, IIa component. (151 aa)    
Predicted Functional Partners:
CBO1991
PTS system, IIbc component.
 
 0.999
pfkB
Probable sugar kinase; This CDS is also similar to CBO1763 (35.644 identity in 303 aa overlap); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.905
fruK
1-phosphofructokinase; This CDS is also similar to CBO1992 (35.644 identity in 303 aa overlap); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.864
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
   
 0.745
CBO3377
Putative ATPase; Displays ATPase and GTPase activities.
  
  
 0.614
ptsH
Putative phosphocarrier protein HPr.
 
  
 0.566
CBO0655
PTS system, beta-glucoside-specific IIabc component.
   
  
 0.519
bglF
PTS system, beta-glucoside-specific IIabc component.
   
  
 0.519
ptsG-2
PTS system, glucose-specific IIABC component.
   
  
 0.519
ptbA-3
Putative PTS system, glucose-specific IIABC component; C-terminal region is similar to Escherichia coli,Escherichia coli O6, and Escherichia coli O157:H7 PTS system, glucose-specific IIBC component PtsG or GlcA or Umg or b1101 or c1373 or z1740 or ecs1479 SWALL:PTGB_ECOLI (SWALL:P05053) (477 aa) fasta scores: E(): 2.6e-50, 42.25 id in 497 aa. Full length CDS is similar to Bacillus subtilis putative PTS system IIABC component YbfS or bsu02350 SWALL:YBFS_BACSU (SWALL:P39816) (631 aa) fasta scores: E(): 4e-56, 41.9 38d in 642 aa.
   
  
 0.519
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.