STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fruAPTS system, IIa component. (151 aa)    
Predicted Functional Partners:
CBO1991
PTS system, IIbc component.
 
 0.999
pfkB
Probable sugar kinase; This CDS is also similar to CBO1763 (35.644 identity in 303 aa overlap); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.915
fruK
1-phosphofructokinase; This CDS is also similar to CBO1992 (35.644 identity in 303 aa overlap); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.878
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.749
CBO3377
Putative ATPase; Displays ATPase and GTPase activities.
  
  
 0.621
raiA
Putative sigma 54 modulation protein/S30EA ribosomal protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
  
  
 0.561
ptsH
Putative phosphocarrier protein HPr.
 
  
 0.558
CBO0655
PTS system, beta-glucoside-specific IIabc component.
   
  
 0.497
bglF
PTS system, beta-glucoside-specific IIabc component.
   
  
 0.497
ptsG-2
PTS system, glucose-specific IIABC component.
   
  
 0.497
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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