STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkBProbable sugar kinase; This CDS is also similar to CBO1763 (35.644 identity in 303 aa overlap); Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (307 aa)    
Predicted Functional Partners:
CBO1991
PTS system, IIbc component.
 
  
 0.999
agaY
Tagatose-1,6-bisphosphate aldolase.
  
 
 0.980
srlD
Sorbitol-6-phosphate 2-dehydrogenase.
  
 
 0.957
fba
Similar to Entamoeba histolytica putative fructose-1,6-bisphosphate aldolase Ald SWALL:Q8MTW2 (EMBL:AY057996) (326 aa) fasta scores: E(): 5.8e-51, 49.2 id in 315 aa, and to Clostridium tetani fructose-bisphosphate aldolase ctc00341 SWALL:Q898U8 (EMBL:AE015937) (320 aa) fasta scores: E(): 3.3e-80,76.75 38d in 314 aa.
  
 
 0.933
tal
Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
   
 
 0.928
CBO2153
Putative transaldolase.
   
 
 0.928
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
  
 0.923
fbp
Fructose-1,6-bisphosphatase.
 
  
 0.922
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.916
manA
Similar to Streptococcus mutans mannose-6-phosphate isomerase Pmi or ManA or smu.1839 SWALL:MANA_STRMU (SWALL:Q59935) (316 aa) fasta scores: E(): 1.1e-29, 35.25 id in 312 aa.
    
 0.915
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (12%) [HD]