STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gldA2Glycerol dehydrogenase; Also similar to CBO0976 (52.5 38d). (363 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
     
 0.920
gldA1
Glycerol dehydrogenase; Also similar to CBO1999 (52.5 38d).
  
  
 
0.903
dkgA
2,5-diketo-D-gluconic acid reductase.
     
 0.900
dhaK
Dihydroxyacetone kinase.
 
 
 0.675
CBO1998
Hypothetical protein; No significant database matches.
       0.501
CBO0062
Putative exported peptidoglycan lytic protein; Similar to Listeria monocytogenes p45 precursor spl or lmo2505 SWALL:Q9RE04 (EMBL:AJ250194) (401 aa) fasta scores: E(): 2.4e-15, 31.18 38d in 388 aa, and to Clostridium acetobutylicum cell wall-associated hydrolase cac0308 SWALL:Q97M90 (EMBL:AE007545) (392 aa) fasta scores: E(): 2.2e-27, 36.84 38d in 380 aa.
      
 0.435
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
      
 0.433
thiC
Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
      
 0.431
CBO3119
Putative FMN-dependent dehydrogenase.
     
 0.431
CBO1270
Putative transporter (partial); Partial CDS. Similar to the N-terminal region of the mentioned database matches; was marked partial.
  
  
 0.413
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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