STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBO2007Putative signaling protein. (182 aa)    
Predicted Functional Partners:
CBO3319
Conserved hypothetical protein; Contains 2 domain matches to Pfam domain PF01966 which usually only occurs in single copies.
 
 
 0.829
CBO0507
Putative metal dependent phosphohydrolase.
 
 
 0.752
CBO0397
Putative metal dependent phosphohydrolase; Similar to Clostridium tetani conserved protein ctc00529 SWALL:Q898D3 (EMBL:AE015937) (357 aa) fasta scores: E(): 7.6e-85, 63.17 38d in 353 aa.
 
 
 0.715
CBO1295
Putative signaling protein.
 
  
 0.654
spoIIR
Similar to Bacillus subtilis stage II sporulation protein R SpoIIR or Ipc-27d or bsu36970 SWALL:SP2R_BACSU (SWALL:P39151) (224 aa) fasta scores: E(): 1.9e-18, 35.71 id in 224 aa, and to Clostridium perfringens stage II sporulation protein R SpoIIR or cpe2211 SWALL:Q8XIB0 (EMBL:AP003193) (209 aa) fasta scores: E(): 1.5e-37,55.34 38d in 206 aa.
      
 0.640
CBO0357
Putative signaling protein; Similar to Chromobacterium violaceum hypothetical protein cv0542 SWALL:AAQ58219 (EMBL:AE016911) (633 aa) fasta scores: E(): 2.3e-57, 35.07 38d in 536 aa.
  
0.602
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
   
 
 0.550
spoIIGA
Putative sporulation sigma-E factor processing peptidase.
      
 0.535
CBO1524
Putative signaling protein.
 
 
0.492
CBO1908
General secretion pathway protein.
  
   
 0.458
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.