STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBO2019Conserved hypothetical protein. (426 aa)    
Predicted Functional Partners:
CBO0105
Conserved hypothetical protein; Similar to Myxococcus xanthus phosphoribosyl amino imidizole carboxylase-like protein SWALL:Q8VQZ2 (EMBL:AF449411) (250 aa) fasta scores: E(): 2.7e-43,52.43 38d in 246 aa, and to Clostridium acetobutylicum ncair mutase cac0776 SWALL:Q97KZ0 (EMBL:AE007592) (248 aa) fasta scores: E(): 4.2e-63, 71.37 38d in 248 aa.
 
  
 0.825
CBO1183
Conserved hypothetical protein.
 
  
 0.728
CBO0104
Conserved hypothetical protein; Similar to Clostridium acetobutylicum ATP-utilizing enzyme of the pp-loop superfamily cac0775 SWALL:Q97KZ1 (EMBL:AE007592) (271 aa) fasta scores: E(): 9.6e-58,59.62 38d in 265 aa, and to Thermoanaerobacter tengcongensis ATP-utilizing enzymes of the pp-loop superfamily tte0769 SWALL:Q8RBP5 (EMBL:AE013044) (255 aa) fasta scores: E(): 7.3e-44, 54.09 38d in 244 aa.
 
  
 0.722
larC
Conserved hypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
  
 0.615
CBO2018
Probable amino acid abc transporter,substrate-binding protein.
       0.552
glcA
Lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
     
 0.471
glcD
Glycolate oxidase subunit.
 
   
 0.453
nifJ2
Pyruvate-flavodoxin oxidoreductase; Also similar to CBO1192 (65.74 38d).
     
 0.453
CBO2017
Probable amino acid ABC transporter, permease protein.
  
    0.444
CBO2016
Probable amino acid ABC transporter, ATP-binding protein.
       0.424
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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