Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO2099Putative proline iminopeptidase. (301 aa)    
Predicted Functional Partners:
pepIP
Proline iminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family.
  
  
 
0.924
prdF
Putative proline racemase; Belongs to the proline racemase family.
     
 0.903
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
 0.902
CBO2470
Conserved hypothetical protein (pseudogene); Similar to Bacillus anthracis Rrf2 family protein ba4743 SWALL:Q81L85 (EMBL:AE017038) (143 aa) fasta scores: E(): 1.9e-20, 48.55 38d in 138 aa. CDS contains a frameshift after codon 88 and nonsense mutations (ochre and opal) after codons 61 and 103. CDS is extended at the N-terminus in comparison to orthologues.
     
  0.900
CBO2471
Conserved hypothetical protein; Identical CBO3191 (99.7), also similar to CBO3190 (53.5) and similar to the upstream CDS (CBO2470, 53.8).
     
  0.900
CBO3190
Conserved hypothetical protein; Identical CBO2471 (99.7), also similar to CBO3191 (53.5) and similar to the upstream CDS (CBO2470, 53.8).
     
  0.900
CBO3191
Conserved hypothetical protein; Identical CBO2470 (99.7), also similar to CBO3190 (53.5) and similar to the upstream CDS (CBO2471, 53.5).
     
  0.900
CBO2098
Putative AraC-family transcriptional regulator.
  
    0.631
CBO2587
Putative AMP-binding enzyme; Similar to an internal region of Bacillus licheniformis bacitracin synthetase 1 BacA SWALL:BACA_BACLI (SWALL:O68006) (5255 aa) fasta scores: E(): 4.3e-49, 33.15 38d in 561 aa.
 
 
 0.578
acdB
acyl-CoA dehydrogenase, short-chain specific.
   
 0.540
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.