Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cutCPutative pyruvate formate-lyase; Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde. Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily. (846 aa)    
Predicted Functional Partners:
cutD
Putative pyruvate formate-lyase activating enzyme; Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).
 
  
 0.942
CBO3184
Putative pyruvate formate-lyase 2 activating enzyme.
 
  
 0.890
CBO2119
Putative aldehyde-alcohol dehydrogenase.
 
  
 0.847
eutT
Conserved hypothetical protein.
 
     0.832
CBO2112
Conserved hypothetical protein.
 
     0.825
CBO2123
Conserved hypothetical protein.
 
     0.825
CBO3579
Putative dehydratase/lyase activating enzyme.
 
  
 0.824
CBO2124
Putative membrane protein.
 
     0.823
act
Formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
 
  
 0.759
eutE
Putative aldehyde-alcohol dehydrogenase.
 
 
 0.740
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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