Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBO2127Putative transmembrane MATE family transporter protein. (433 aa)    
Predicted Functional Partners:
CBO0364
Putative phosphatase; Similar to Clostridium tetani ser/thr and tyr protein phosphatase ctc02044 SWALL:Q892P9 (EMBL:AE015943) (208 aa) fasta scores: E(): 6e-36, 43.35 38d in 203 aa.
   
    0.521
CBO2128
Putative MarR-family transcriptional regulator.
  
    0.494
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
  
 0.481
gap1
Similar to Bacillus megaterium glyceraldehyde 3-phosphate dehydrogenase Gap SWALL:G3P_BACME (SWALL:P23722) (334 aa) fasta scores: E(): 4.3e-78, 64.86 id in 333 aa, and to Bacillus stearothermophilus glyceraldehyde 3-phosphate dehydrogenase Gap SWALL:G3P_BACST (SWALL:P00362) (334 aa) fasta scores: E(): 4.1e-82, 69.06 38d in 333 aa; Also similar to CBO1095 (66.26 38d).
   
    0.456
gapA2
Glyceraldehyde 3-phosphate dehydrogenase A; Also similar to CBO0226 (66.26 38d); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
    0.456
CBO0072
Putative Na+ driven multidrug efflux pump; Similar to Vibrio parahaemolyticus multidrug resistance protein NorM or vp1479 SWALL:NORM_VIBPA (SWALL:O82855) (456 aa) fasta scores: E(): 8.1e-23, 26.57 id in 414 aa, and to Clostridium tetani Na+ driven multidrug efflux pump ctc01799 SWALL:Q893L8 (EMBL:AE015942) (455 aa) fasta scores: E(): 6.5e-93,52.71 38d in 442 aa.
  
     0.418
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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