STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO2138Putative membrane protein; N-terminus to codon 245 is similar to Clostridium tetani hypothetical protein ctc00646 SWALL:Q897T1 (EMBL:AE015938) (234 aa) fasta scores: E(): 0.023, 21.75 id in 216 aa, and the C-terminus from codon 245 is similar to Thermoanaerobacter tengcongensis aminopeptidase N PepN or tte2694 SWALL:Q8R6U0 (EMBL:AE013209) (479 aa) fasta scores: E(): 0.0027, 21.49 38d in 507 aa. CDS overlaps CBO2137 8 nt at the C-terminus. (741 aa)    
Predicted Functional Partners:
CBO2139
ABC transporter, ATP-binding protein.
 
 
   0.921
CBO2137
Putative membrane protein; CDS overlaps CBO2138 8 nt at the N-terminus.
     
 0.831
fldZ
Cinnamate reductase; This enzyme was purified from C. sporogenes and its N-terminus sequenced (Dickert et al. 2000 Eur. J. Biochem. 267, 3874-3884.
 
 
 0.664
CBO2140
Putative ABC transporter, permease protein.
       0.600
tetM
Putative tetracycline resistance protein.
   
 
 0.571
fusA
Translation elongation factor G, Ef-G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/ [...]
   
 
 0.571
fusB
Translation elongation factor G, Ef-G.
   
 
 0.571
dnaK
Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.503
CBO3578
Conserved hypothetical protein.
  
     0.491
CBO2135
Two-component sensor kinase.
  
 
 0.478
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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