STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CBO2156Putative membrane protein. (197 aa)    
Predicted Functional Partners:
plsX
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
  
 0.986
gpsA
Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
 
 0.961
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
    
 0.932
plsD
Probable acyltransferase; Similar to Clostridium butyricum sn-glycerol-3-phosphate acyltransferase plsD SWALL:O32330 (EMBL:AF009362) (234 aa) fasta scores: E(): 9e-45, 56.65 id in 233 aa.
  
 
 0.929
CBO0416
Probable acyltransferase; Similar to Escherichia coli 1-acyl-sn-glycerol-3-phosphate acyltransferase PlsC or ParF or b3018 SWALL:PLSC_ECOLI (SWALL:P26647) (245 aa) fasta scores: E(): 1.9e-09, 28.8 38d in 184 aa, and to Clostridium tetani putative 1-acyl-sn-glycerol-3-phosphate acyltransferase ctc00551 SWALL:Q898B3 (EMBL:AE015937) (242 aa) fasta scores: E(): 3.9e-41, 45.57 38d in 237 aa.
  
 
 0.929
glpA
Putative anaerobic glycerol-3-phosphate dehydrogenase subunit a.
    
 0.901
CBO2244
Putative anaerobic glycerol-3-phosphate dehydrogenase protein.
    
 0.901
cinA
Putative molybdopterin binding; Similar to Bacillus subtilis cina-like protein CinA or bsu16930 SWALL:CINA_BACSU (SWALL:P46323) (416 aa) fasta scores: E(): 6.2e-57, 44.92 38d in 394 aa, and to Clostridium acetobutylicum competence-damage inducible protein, cina cac3586 SWALL:Q97D94 (EMBL:AE007855) (411 aa) fasta scores: E(): 1.3e-92, 60.29 38d in 408 aa; Belongs to the CinA family.
 
   
 0.557
topB
Putative DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...]
     
 0.537
topA
Putative DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing [...]
     
 0.537
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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