Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO2164AraC family regulatory protein; N-terminal region is similar to Escherichia coli,Escherichia coli O6, and Escherichia coli O157:H7 regulatory protein SoxS or b4062 or c5053 or z5661 or ecs5044 SWALL:SOXS_ECOLI (SWALL:P22539) (106 aa) fasta scores: E(): 7.2e-08, 32.07 38d in 106 aa. Full length CDS is similar to Clostridium tetani transcriptional regulatory protein ctc01432 SWALL:Q894V2 (EMBL:AE015941) (295 aa) fasta scores: E(): 1.9e-78, 64.4 38d in 295 aa. (296 aa)    
Predicted Functional Partners:
CBO2163
Hypothetical protein.
 
     0.826
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.805
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.712
sigA
RNA polymerase sigma factor (sigma-43); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.657
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.635
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.635
CBO0305
Similar to Clostridium tetani transcriptional regulatory protein ctc00913 SWALL:Q896T5 (EMBL:AE015939) (334 aa) fasta scores: E(): 1.4e-09, 26.42 38d in 333 aa.
  
     0.604
CBO2781
AraC-family transcriptional regulator.
 
 
 0.568
CBO1598
AraC-family transcriptional regulator.
  
     0.537
CBO0308
Similar to Clostridium tetani transcriptional regulatory protein ctc01411 SWALL:Q894X3 (EMBL:AE015941) (329 aa) fasta scores: E(): 7.3e-10, 22.29 38d in 323 aa.
  
     0.526
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.