STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBO2167MerR family regulatory protein. (265 aa)    
Predicted Functional Partners:
CBO2168
Putative membrane protein; No significant database matches.
       0.629
CBO2169
Hypothetical protein; No significant database matches.
       0.625
fldZ
Cinnamate reductase; This enzyme was purified from C. sporogenes and its N-terminus sequenced (Dickert et al. 2000 Eur. J. Biochem. 267, 3874-3884.
  
  
 0.606
CBO2170
Hypothetical protein; No significant database matches.
       0.534
CBO2171
Hypothetical protein; Weakly similar to Porphyromonas gingivalis CRISPR-associated protein, TM1791 family PG1983 SWALL:AAQ66956 (EMBL:AE017178) (253 aa) fasta scores: E(): 3.4e-08, 34.85 38d in 307 aa.
       0.527
CBO2172
Hypothetical protein.
       0.520
CBO0189
DnaJ-related protein; Similar to Clostridium acetobutylicum molecular chaperone, DNAJ family cac0648 SWALL:Q97LB4 (EMBL:AE007580) (195 aa) fasta scores: E(): 1.6e-36,55.15 38d in 194 aa.
  
 
 0.473
dnaJ
Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...]
  
 
 0.473
CBO2173
Conserved hypothetical protein.
       0.469
CBO2174
Conserved hypothetical protein.
       0.464
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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