Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBO2236Putative short chain dehydrogenase; Weakly similar to the C-terminal region of Rattus norvegicus D-beta-hydroxybutyrate dehydrogenase,mitochondrial precursor BDH SWALL:BDH_RAT (SWALL:P29147) (344 aa) fasta scores: E(): 3.1e-09, 25.65 38d in 269 aa. Similar to the full length Pseudomonas aeruginosa probable short-chain dehydrogenase PA1330 SWALL:Q9I414 (EMBL:AE004562) (259 aa) fasta scores: E(): 5.4e-22,33.85 38d in 254 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (265 aa)    
Predicted Functional Partners:
CBO2584
Putative chain-fatty-acid-CoA ligase.
  
 
 0.695
fldL
Putative CoA-ligase.
  
 
 0.695
CBO2587
Putative AMP-binding enzyme; Similar to an internal region of Bacillus licheniformis bacitracin synthetase 1 BacA SWALL:BACA_BACLI (SWALL:O68006) (5255 aa) fasta scores: E(): 4.3e-49, 33.15 38d in 561 aa.
 
  
 0.635
srlD
Sorbitol-6-phosphate 2-dehydrogenase.
 
 
 0.586
fabG
3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.533
CBO2718
Glucose-1-phosphate cytidylyltransferase.
   
 
 0.489
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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