STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO2245MerR family regulatory protein. (272 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.822
sigA
RNA polymerase sigma factor (sigma-43); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.817
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.800
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.800
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.798
CBO0710
Putative drug resistance ABC-transporter,membrane protein.
 
    0.654
CBO0708
MerR-family transcriptional regulator.
  
     0.641
CBO0716
Putative transcriptional regulator (partial); Partial CDS. Similar to the C-terminal region of Clostridium tetani putative transcriptional regulatory protein ctc01439 SWALL:Q894U5 (EMBL:AE015941) (235 aa) fasta scores: E(): 2.1e-12, 41.81 38d in 110 aa; was marked partial.
 
     0.618
CBO1995
Conserved hypothetical protein.
 
     0.547
CBO0443
Similar to Methanosarcina mazei conserved protein mm1395 SWALL:Q8PX27 (EMBL:AE013374) (154 aa) fasta scores: E(): 8e-25, 48.36 38d in 153 aa.
 
   
 0.524
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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