STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBO2263Metallopeptidase family M24 protein; Similar to an internal region of Homo sapiens xaa-Pro aminopeptidase 2 precursor XPNPEP2 SWALL:XPP2_HUMAN (SWALL:O43895) (674 aa) fasta scores: E(): 1.1e-58, 31.58 38d in 611 aa. Similar to full length Clostridium perfringens probable aminopeptidase CPE0872 SWALL:Q8XM18 (EMBL:AP003188) (591 aa) fasta scores: E(): 1.8e-101, 45.22 38d in 597 aa. (597 aa)    
Predicted Functional Partners:
CBO2264
Putative oligopeptide transporter.
 
   
 0.722
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
  
 
 0.600
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.590
nifJ2
Pyruvate-flavodoxin oxidoreductase; Also similar to CBO1192 (65.74 38d).
     
 0.560
lepB-2
Putative signal peptidase I; Belongs to the peptidase S26 family.
 
  
 0.557
nifJ1
Putative pyruvate-flavodoxin oxidoreductase; Also similar to CBO2760 (65.74 38d).
  
  
 0.554
map2
Methionine aminopeptidase 2; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
 
  
 0.535
CBO0146
Putative zinc-binding protein; Similar to Clostridium tetani comE operon protein 2 ctc00309 SWALL:Q898X8 (EMBL:AE015936) (162 aa) fasta scores: E(): 6.7e-56, 81.48 38d in 162 aa, and to Clostridium acetobutylicum deoxycytidylate deaminase cac2876 SWALL:Q97F76 (EMBL:AE007785) (162 aa) fasta scores: E(): 1.9e-44, 67.28 38d in 162 aa.
  
    0.512
CBO2262
Putative membrane protein.
       0.508
lepB
Signal peptidase; Belongs to the peptidase S26 family.
   
  
 0.479
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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