Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CBO2294Putative membrane protein. (198 aa)    
Predicted Functional Partners:
glpF
Glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
 
 0.625
CBO2505
Putative protein phosphatase.
    
   0.619
CBO1754
Putative phage protein.
  
     0.569
ppiB
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.539
CBO1003
Putative ATPase.
    
   0.534
CBO0189
DnaJ-related protein; Similar to Clostridium acetobutylicum molecular chaperone, DNAJ family cac0648 SWALL:Q97LB4 (EMBL:AE007580) (195 aa) fasta scores: E(): 1.6e-36,55.15 38d in 194 aa.
    
 
 0.492
dnaJ
Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...]
    
 
 0.492
adK
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
   0.490
CBO0299
Putative dolichyl-phosphate-mannose-protein mannosyltransferase; Similar to Streptomyces carzinostaticus subsp. neocarzinostaticus membrane protein SWALL:Q84HC4 (EMBL:AY117439) (720 aa) fasta scores: E(): 2.4e-25,27.37 38d in 767 aa.
  
     0.409
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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