Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ftsKDNA translocase FtsK. (758 aa)    
Predicted Functional Partners:
spo0J
Stage 0 sporulation protein J; Also similar to CBO3640 (44.488 38d. in 254 aa overlap); Belongs to the ParB family.
  
  
 0.822
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.811
divIB
Cell division protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
  
 
 0.781
xerD2
Tyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family.
 
   
 0.772
noc
Chromosome partitioning protein (putative stage 0 sporulation protein J); Also similar to CBO3638 (44.488 38d. in 254 aa overlap); Belongs to the ParB family.
  
  
 0.768
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
  
 0.764
recJ
single-stranded-DNA-specific exonuclease.
 
  
 0.741
CBO1056
Putative glycosyltransferase (gene fragment); Pfam match to entry PF00534 Glycos_transf_1,Glycosyl transferases group 1, score 42.2, E-value 2.3e-11.
   
 
 0.721
CBO1208
Conserved hypothetical protein.
   
 
 0.721
CBO2779
Putative membrane protein; No significant database matches.
   
 
 0.721
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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