Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO2465Hypothetical protein; No significant database matches. (56 aa)    
Predicted Functional Partners:
prdA1
Putative proline reductase protein; Highly similar to CBO2480 (84.5 38d), CBO2483 (63.9 38d).
 
   
 0.938
CBO2463
Conserved hypothetical protein.
 
   
 0.931
prdC1
Putative electron transferring subunit of proline reductase; Similar to the N-terminal region of Clostridium sticklandii electron transfer protein PrdC SWALL:Q9L4Q5 (EMBL:AJ130879) (402 aa) fasta scores: E(): 6e-59, 47.13 id in 367 aa.
 
   
 0.925
rnfB
Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
  
 
 0.915
prdB1
Similar to Clostridium sticklandii proline reductase PrdB SWALL:Q9Z4Q7 (EMBL:AJ130879) (242 aa) fasta scores: E(): 8.5e-70, 79.07 38d in 239 aa. CDS contains an in frame UGA codon for probable selenocysteine insertion.
 
   
 0.915
rnfD
Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.
  
 
 0.895
rnfG
Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
  
 
 0.866
rnfE
Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
  
 
 0.844
CBO2479
Conserved hypothetical protein.
 
   
 0.807
prdD
Putative component of proline reductase.
 
   
 0.801
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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