Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
CBO2473Putative integral membrane protein. (289 aa)    
Predicted Functional Partners:
prdE
Putative component of proline reductase.
 
     0.773
prdD
Putative component of proline reductase.
 
     0.769
prdA1
Putative proline reductase protein; Highly similar to CBO2480 (84.5 38d), CBO2483 (63.9 38d).
 
     0.760
prdA2
Putative subunit of proline reductase.
 
     0.759
CBO2479
Conserved hypothetical protein.
 
     0.749
CBO2463
Conserved hypothetical protein.
 
     0.734
prdB2
Putative subunit of proline reductase; Similar to Clostridium sticklandii proline reductase PrdB SWALL:Q9Z4Q7 (EMBL:AJ130879) (242 aa) fasta scores: E(): 1.1e-71, 80.33 38d in 239 aa. CDS contains an in frame UGA codon for probable selenocysteine insertion.
 
     0.709
prdB1
Similar to Clostridium sticklandii proline reductase PrdB SWALL:Q9Z4Q7 (EMBL:AJ130879) (242 aa) fasta scores: E(): 8.5e-70, 79.07 38d in 239 aa. CDS contains an in frame UGA codon for probable selenocysteine insertion.
 
     0.707
CBO0183
Putative pyridine nucleotide-disulphide oxidoreductase; Similar to Fusobacterium nucleatum coenzyme a disulfide reductase/ disulfide bond regulator domain fn1903 SWALL:Q8RHU1 (EMBL:AE010492) (810 aa) fasta scores: E(): 1e-163, 56.35 38d in 818 aa, and to Fusobacterium nucleatum subsp. vincentii ATCC 49256 coenzyme a disulfide reductase/ disulfide bond regulator domain fnv2089 SWALL:Q7P7P1 (EMBL:AABF01000012) (809 aa) fasta scores: E(): 2.7e-159, 55.5 38d in 818 aa; Belongs to the sulfur carrier protein TusA family.
  
  
 0.623
prdC3
Putative proline reductase (partial); Similar to the N-terminal region of Clostridium sticklandii proline reductase proprotein, two subunits PrdA SWALL:Q9Z4P6 (EMBL:AJ130879) (630 aa) fasta scores: E(): 9.2e-15, 33.94 38d in 218 aa. Possible gene remnant; was marked partial.
 
    0.595
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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