Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO2479Conserved hypothetical protein. (91 aa)    
Predicted Functional Partners:
prdA2
Putative subunit of proline reductase.
 
   
 0.956
CBO2481
Hypothetical protein; No significant database matches.
 
   
 0.940
prdC2
Putative electron transferring subunit of proline reductase; Similar to the N-terminal region of Clostridium sticklandii electron transfer protein PrdC SWALL:Q9L4Q5 (EMBL:AJ130879) (402 aa) fasta scores: E(): 9.7e-61,48.77 38d in 367 aa.
 
   
 0.920
prdB2
Putative subunit of proline reductase; Similar to Clostridium sticklandii proline reductase PrdB SWALL:Q9Z4Q7 (EMBL:AJ130879) (242 aa) fasta scores: E(): 1.1e-71, 80.33 38d in 239 aa. CDS contains an in frame UGA codon for probable selenocysteine insertion.
 
   
 0.916
prdD
Putative component of proline reductase.
 
   
 0.881
prdE
Putative component of proline reductase.
 
   
 0.871
prdA1
Putative proline reductase protein; Highly similar to CBO2480 (84.5 38d), CBO2483 (63.9 38d).
 
   
 0.817
prdB1
Similar to Clostridium sticklandii proline reductase PrdB SWALL:Q9Z4Q7 (EMBL:AJ130879) (242 aa) fasta scores: E(): 8.5e-70, 79.07 38d in 239 aa. CDS contains an in frame UGA codon for probable selenocysteine insertion.
 
   
 0.815
CBO2465
Hypothetical protein; No significant database matches.
 
   
 0.807
prdC3
Putative proline reductase (partial); Similar to the N-terminal region of Clostridium sticklandii proline reductase proprotein, two subunits PrdA SWALL:Q9Z4P6 (EMBL:AJ130879) (630 aa) fasta scores: E(): 9.2e-15, 33.94 38d in 218 aa. Possible gene remnant; was marked partial.
 
   
 0.794
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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