Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
tmcALConserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (409 aa)    
Predicted Functional Partners:
CBO0060
Conserved hypothetical protein; Similar to Clostridium acetobutylicum SAM-dependent methyltransferase cac0306 SWALL:Q97M92 (EMBL:AE007545) (244 aa) fasta scores: E(): 1e-56, 61.47 38d in 244 aa,and to Clostridium perfringens hypothetical protein Cpe0279 SWALL:Q8XNQ3 (EMBL:AP003186) (256 aa) fasta scores: E(): 1e-52, 57.61 38d in 243 aa.
 
     0.738
ylbJ
Putative membrane protein.
  
    0.725
CBO3144
Conserved hypothetical protein.
  
    0.644
polC
DNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
     0.626
ecfT
ABC transporter, permease protein; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
     0.587
CBO2983
Putative phosphohydrolase.
 
  
 0.544
CBO2713
Putative methyltransferase.
  
    0.518
CBO2716
Putative methyltransferase.
  
    0.518
CBO3623
Putative phosphoesterase; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
     0.497
CBO2453
Radical SAM superfamily protein.
 
     0.440
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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