STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpePutative ribulose-phosphate 3-epimerase; Similar to the C-terminal region of Solanum tuberosum ribulose-phosphate 3-epimerase, chloroplast precursor SWALL:RPE_SOLTU (SWALL:Q43843) (280 aa) fasta scores: E(): 1.7e-34, 51.4 38d in 214 aa. (216 aa)    
Predicted Functional Partners:
tkt-2
Transketolase, thiamine disphosphate-bindin subunit; Similar to the N-terminal region of several transketolase including Homo sapiens transketolase Tkt or Tkt1 SWALL:TKT_HUMAN (SWALL:P29401) (623 aa) fasta scores: E(): 3.8e-36, 42.85 38d in 273 aa.
  
 0.995
rpiB
Similar to Escherichia coli ribose 5-phosphate isomerase B RpiB or b4090 SWALL:RPIB_ECOLI (SWALL:P37351) (149 aa) fasta scores: E(): 2.2e-27, 52.77 38d in 144 aa,and to Clostridium tetani ribose 5-phosphate isomerase ctc00307 SWALL:Q898Y0 (EMBL:AE015936) (149 aa) fasta scores: E(): 1.5e-43, 78.47 38d in 144 aa.
  
 
 0.951
tkt
Transketolase, pyridine binding subunit; Similar to C-terminal region of several transketolases including Homo sapiens transketolase Tkt or Tkt1 SWALL:TKT_HUMAN (SWALL:P29401) (623 aa) fasta scores: E(): 6e-37, 40.69 38d in 317 aa.
 
 
 0.950
rsgA
Conserved hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
  
  
 0.940
CBO2501
Conserved hypothetical protein.
  
  
 0.885
kdgK
Similar to Escherichia coli 2-dehydro-3-deoxygluconokinase KdgK or b3526 SWALL:KDGK_ECOLI (SWALL:P37647) (309 aa) fasta scores: E(): 2e-08, 26.46 38d in 291 aa.
  
 0.854
pgK
Phosphoglycerate kinase; Similar to Bacillus megaterium phosphoglycerate kinase Pgk SWALL:PGK_BACME (SWALL:P24269) (394 aa) fasta scores: E(): 2.4e-80, 57.07 38d in 396 aa, and to Clostridium acetobutylicum phosphoglycerate kinase Pgk or cac0710 SWALL:PGK_CLOAB (SWALL:O52632) (397 aa) fasta scores: E(): 5.4e-110, 77.44 38d in 399 aa.
 
 
 0.710
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 
 0.708
rsmB
Putative ribosomal RNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
   0.706
rbr
Putative rubrerythrin.
      
 0.681
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.