Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBO2569RRF2 family regulatory protein. (148 aa)    
Predicted Functional Partners:
iscS-2
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
  
 0.932
nifU
Conserved hypothetical protein; Similar to the N-terminal region of Azotobacter vinelandii nitrogen fixation protein NifU SWALL:NIFU_AZOVI (SWALL:P05340) (312 aa) fasta scores: E(): 1e-21, 52.94 id in 119 aa. Full length CDS is similar to Clostridium perfringens probable nitrogen fixation protein NifU or CPE1784 SWALL:Q8XJH2 (EMBL:AP003191) (142 aa) fasta scores: E(): 1.3e-45, 82.27 38d in 141 aa.
 
  
 0.930
iscS
Cysteine desulfurase.
 
  
 0.720
CBO2566
Conserved hypothetical protein.
       0.587
CBO2565
Putative membrane protein.
       0.581
CBO2570
Putative ATPase.
       0.572
alaS
Putative alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
       0.448
CBO2571
Conserved hypothetical protein; Belongs to the PHP hydrolase family. HisK subfamily.
 
     0.436
CBO2563
Conserved hypothetical protein; Belongs to the UPF0297 family.
       0.405
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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