Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arcBOrnithine carbamoyltransferase chain I; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (333 aa)    
Predicted Functional Partners:
arcC
Putative carbamate kinase; Belongs to the carbamate kinase family.
 
 0.998
arcA1
Arginine deiminase; Similar to Enterococcus faecalis arginine deiminase ArcA or ef0104 SWALL:Q93K67 (EMBL:AJ312276) (408 aa) fasta scores: E(): 1.6e-80, 55.06 38d in 405 aa, and to Bacillus licheniformis arginine deiminase ArcA SWALL:ARCA_BACLI (SWALL:O86131) (413 aa) fasta scores: E(): 3.7e-77, 51.22 id in 408 aa; Also similar to CBO1587 (57.03 38d).
 
 
 0.993
arcA2
Arginine deiminase; Also similar to CBO0065 (57.03 38d).
 
 
 0.993
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.987
CBO2723
Conserved hypothetical protein.
  
 
 0.948
argH
Argininosuccinate lyase.
 
  
 0.898
pyrB
Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
0.865
pyrI
Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.
 
  
  0.857
argR
Arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.771
CBO1656
Putative membrane protein; Also similar to CBO2229 (57.84 38d).
  
  
 0.636
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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