STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBO2753Conserved hypothetical protein. (677 aa)    
Predicted Functional Partners:
cheW
Chemotaxis protein CheW.
 
    0.885
cheD
Chemotaxis protein CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
     0.867
cheR
Chemotaxis protein methyltransferase.
 
     0.829
cheC
Chemotaxis protein CheC.
 
    0.820
cheN
Chemotaxis protein CheA.
 
    0.820
cheB
Chemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
       0.803
fliM
Flagellar motor switch protein FliM.
 
     0.800
fliY
Flagellar motor switch protein FliY.
 
    0.746
CBO2745
Similar to Clostridium tetani putative chemotaxis protein CTC01728 SWALL:Q893T1 (EMBL:AE015942) (134 aa) fasta scores: E(): 1.6e-30, 67.93 38d in 131 aa. Similar to an internal region of Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri chemotaxis protein CheW or b1887 or c2302 or z2941 or ecs2597 or sf1936 or s2027 SWALL:CHEW_ECOLI (SWALL:P07365) (167 aa) fasta scores: E(): 1.5e-08, 31.34 38d in 134 aa.
 
    0.694
fliW
Putative flagella-related conserved hypothetical protein; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
     0.666
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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