Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
recJsingle-stranded-DNA-specific exonuclease. (593 aa)    
Predicted Functional Partners:
polC
DNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
     
 0.773
ftsK
DNA translocase FtsK.
 
  
 0.741
CBO0332
Putative accessory gene regulator protein B; Similar to Clostridium perfringens hypothetical protein Cpe1561 SWALL:Q8XK42 (EMBL:AP003191) (214 aa) fasta scores: E(): 1.3e-33, 44.39 38d in 214 aa.
      
 0.703
CBO2764
Putative endonuclease.
  
  
 0.701
xerD2
Tyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family.
  
  
 0.697
CBO0338
Putative accessory gene regulator protein B; Similar to Clostridium perfringens hypothetical protein Cpe1561 SWALL:Q8XK42 (EMBL:AP003191) (214 aa) fasta scores: E(): 8.7e-24, 35.92 38d in 206 aa.
      
 0.688
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
  
 0.624
dprA
SMF family protein; C-terminus is similar to the C-terminal region of Haemophilus influenzae Smf protein HI0985 SWALL:SMF_HAEIN (SWALL:P43862) (373 aa) fasta scores: E(): 3e-26, 35.64 id in 317 aa, and to Clostridium tetani Smf protein,putative DNA processing chain A CTC01258 SWALL:Q895L5 (EMBL:AE015940) (361 aa) fasta scores: E(): 1.5e-65,54.69 38d in 362 aa.
 
   
 0.587
priA
Putative primosomal protein n'(replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
     0.570
CBO2762
Putative sensory transduction histidine kinase.
 
     0.570
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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