Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glpPGlycerol uptake operon antiterminator regulatory protein. (187 aa)    
Predicted Functional Partners:
CBO1070
Conserved hypothetical protein.
 
    0.775
glpF
Glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
  
 0.755
glpA
Putative anaerobic glycerol-3-phosphate dehydrogenase subunit a.
 
     0.750
CBO3315
Putative oxidoreductase.
 
    0.746
CBO2244
Putative anaerobic glycerol-3-phosphate dehydrogenase protein.
 
     0.729
CBO0013
Similar to Clostridium acetobutylicum predicted dehydrogenase with iron-sulfur domain cac0012 SWALL:Q97N26 (EMBL:AE007514) (467 aa) fasta scores: E(): 1.2e-65,44.63 38d in 475 aa, and to Clostridium tetani dehydrogenase, fad-dependent ctc00083 SWALL:Q899T4 (EMBL:AE015936) (475 aa) fasta scores: E(): 2.7e-91,55.48 38d in 465 aa.
 
     0.725
CBO0014
Similar to Clostridium tetani conserved protein ctc00082 SWALL:Q899T5 (EMBL:AE015936) (133 aa) fasta scores: E(): 1.6e-25, 59.01 38d in 122 aa, and to Clostridium acetobutylicum uncharacterized small conserved protein, ortholog of t.maritima cac0013 SWALL:Q97N25 (EMBL:AE007514) (76 aa) fasta scores: E(): 3.4e-16, 76.38 id in 72 aa.
 
    0.725
pyrR
Putative pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
      
 0.718
gyrA-2
DNA gyrase subunit A.
       0.707
rimP
Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
      
 0.694
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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