STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (244 aa)    
Predicted Functional Partners:
nagA
N-acetylglucosamine-6-phosphate deacetylase.
 0.999
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.944
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
  
 
 0.939
glmS
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.935
manA
Similar to Streptococcus mutans mannose-6-phosphate isomerase Pmi or ManA or smu.1839 SWALL:MANA_STRMU (SWALL:Q59935) (316 aa) fasta scores: E(): 1.1e-29, 35.25 id in 312 aa.
     
 0.922
ptsG-2
PTS system, glucose-specific IIABC component.
 
  
 0.733
CBO0655
PTS system, beta-glucoside-specific IIabc component.
  
  
 0.730
bglF
PTS system, beta-glucoside-specific IIabc component.
  
  
 0.730
ptbA-3
Putative PTS system, glucose-specific IIABC component; C-terminal region is similar to Escherichia coli,Escherichia coli O6, and Escherichia coli O157:H7 PTS system, glucose-specific IIBC component PtsG or GlcA or Umg or b1101 or c1373 or z1740 or ecs1479 SWALL:PTGB_ECOLI (SWALL:P05053) (477 aa) fasta scores: E(): 2.6e-50, 42.25 id in 497 aa. Full length CDS is similar to Bacillus subtilis putative PTS system IIABC component YbfS or bsu02350 SWALL:YBFS_BACSU (SWALL:P39816) (631 aa) fasta scores: E(): 4e-56, 41.9 38d in 642 aa.
 
  
 0.730
glmU
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
  
  
 0.713
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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