Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptbA-4Pts system, IIa component. (159 aa)    
Predicted Functional Partners:
nagE
PTS system, N-acetylglucosamine-specific IIabc component.
 
 0.983
CBO0268
Similar to Escherichia coli PTS system, maltose and glucose-specific IIabc component MalX or b1621 SWALL:PTOA_ECOLI (SWALL:P19642) (530 aa) fasta scores: E(): 6.6e-55, 40.03 38d in 522 aa.
 
 0.981
CBO1605
PTS system, IIbc component.
 
 0.981
CBO0288
Similar to Escherichia coli PTS system, maltose and glucose-specific IIabc component MalX or b1621 SWALL:PTOA_ECOLI (SWALL:P19642) (530 aa) fasta scores: E(): 1.5e-62, 38.43 38d in 523 aa, and to Bacillus subtilis PTS system, arbutin-like IIbc component GlvC or GlvCB or glv-2 or bsu08200 SWALL:PTIB_BACSU (SWALL:P54715) (527 aa) fasta scores: E(): 5.1e-61, 37.73 38d in 530 aa; Also highly similar to CBO0277 (53.2 38d).
 
 0.980
CBO0277
Similar to Bacillus subtilis PTS system,arbutin-like IIbc component GlvC or GlvCB or Glv-2 or bsu08200 SWALL:PTIB_BACSU (SWALL:P54715) (527 aa) fasta scores: E(): 8.6e-61, 36.41 38d in 530 aa, and to Klebsiella pneumoniae PTS system, alpha-glucoside-specific IIbc component AglA SWALL:PTAB_KLEPN (SWALL:Q9AGA7) (540 aa) fasta scores: E(): 3.3e-59, 35.53 38d in 529 aa; Also highly similar to CBO0288 (53.2 38d).
 
 0.979
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.975
CBO1344
PTS system, IIbc component.
 
 0.964
treB
PTS system, trehalose-specific IIbc component.
 
 0.957
bglF
PTS system, beta-glucoside-specific IIabc component.
 
 
0.582
CBO0655
PTS system, beta-glucoside-specific IIabc component.
 
 
0.576
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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