Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nagEPTS system, N-acetylglucosamine-specific IIabc component. (480 aa)    
Predicted Functional Partners:
ptsG
Similar to Bacillus subtilis PTS system,glucose-specific IIabc component PtsG or PtsX or Crr or bsu13890 SWALL:PTGA_BACSU (SWALL:P20166) (699 aa) fasta scores: E(): 3.7e-24, 52.56 38d in 156 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri PTS system, glucose-specific IIa component Crr or Gsr or Iex or Tgs or TreD or b2417 or c2952 or sf2472 or s2618 SWALL:PTGA_ECOLI (SWALL:P08837) (168 aa) fasta scores: E(): 2.1e-22, 42.35 38d in 170 aa.
 0.998
ptbA
Similar to Salmonella typhimurium, and Salmonella typhi PTS system, glucose-specific IIa component Crr or stm2433 or sty2670 or t0424 SWALL:PTGA_SALTY (SWALL:P02908) (168 aa) fasta scores: E(): 1.4e-13, 40.58 id in 138 aa.
 0.997
ptbA-2
PTS system, IIa component; Similar to Salmonella typhimurium, and Salmonella typhi PTS system, glucose-specific IIa component crr or stm2433 or sty2670 or t0424 SWALL:PTGA_SALTY (SWALL:P02908) (168 aa) fasta scores: E(): 3.7e-15, 40 38d in 150 aa.
 0.996
ptbA-4
Pts system, IIa component.
 
 0.983
nagA
N-acetylglucosamine-6-phosphate deacetylase.
 
  
 0.934
murQ
Putative phosphosugar binding/isomerase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.
  
 
 0.928
ptsH
Putative phosphocarrier protein HPr.
  
 
 0.921
CBO1201
Putative sugar kinase.
  
 
 0.828
glcK
Putative glucokinase.
  
 
 0.828
CBO0655
PTS system, beta-glucoside-specific IIabc component.
 
 
 0.733
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (18%) [HD]