Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ctfAButyrate-acetoacetate CoA-transferase subunit A. (238 aa)    
Predicted Functional Partners:
ctfB
Butyrate-acetoacetate CoA-transferase subunit B.
 0.999
thl
acetyl-CoA acetyltransferase (thiolase); Belongs to the thiolase-like superfamily. Thiolase family.
 
 
 0.979
adhE
Similar to Clostridium acetobutylicum aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase [acetylating] (EC 1.2.1.10) (acdh); pyruvate-formate-lyase deactivase (pfl deactivase)] AdhE or Aad or cap0162 SWALL:ADHE_CLOAB (SWALL:P33744) (862 aa) fasta scores: E(): 2.6e-212,65.04 38d in 861 aa, and to Escherichia coli, and Escherichia coli O157:H7 aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase [acetylating] (EC 1.2.1.10) (acdh); pyruvate-formate-lyase deactivase (pfl deactivase)] AdhE or Ana or b1241 or z20 [...]
  
 
 0.969
hbd
3-hydroxybutyryl-CoA dehydrogenase.
  
 
 0.954
bcd
butyryl-CoA dehydrogenase.
  
 
 0.947
buk1
Butyrate kinase 1; Also similar to CBO3428 (57.670 38d. in 352 aa overlap); Belongs to the acetokinase family.
     
 0.939
buk2
Butyrate kinase 2; Also similar to CBO3426 (57.670 38d. in 352 aa overlap); Belongs to the acetokinase family.
     
 0.939
ptb2
Phosphate butyryltransferase; Also similar to CBO3118 (53.37 38d).
    
 0.938
eutE
Putative aldehyde-alcohol dehydrogenase.
  
 
 0.915
ptb1
Phosphate butyryltransferase; Also similar to CBO3427 (53.37 38d).
    
 0.902
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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