Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pepDAminoacyl-histidine dipeptidase. (478 aa)    
Predicted Functional Partners:
pepD-2
Putative aminoacyl-histidine dipeptidase.
  
  
 
0.906
pepD-3
Putative aminoacyl-histidine dipeptidase.
  
  
 
0.901
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.844
aspC
Aspartate aminotransferase.
 
 
  0.841
metC
Cystathionine beta-lyase.
    
  0.811
CBO1014
Putative aromatic amino acid aminotransferase.
   
  0.810
aspC-2
Aspartate aminotransferase.
   
  0.810
CBO1400
Putative aminotransferase.
    
  0.805
CBO1963
Putative aminotransferase.
    
  0.805
cysK1
Cysteine synthase 1; Also similar to CBO0205 (53.5 38d); Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.802
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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