Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
mgtAMg(2+) transport atpase, P-type 1. (881 aa)    
Predicted Functional Partners:
CBO0093
Putative cations transporter; Similar to Bacillus subtilis SapB protein or bsu06650 SWALL:SAPB_BACSU (SWALL:Q45514) (232 aa) fasta scores: E(): 7.7e-13, 28.15 38d in 206 aa, and to Clostridium perfringens probable Mg2+ transport protein cpe0592 SWALL:Q8XMU6 (EMBL:AP003187) (241 aa) fasta scores: E(): 1.2e-27, 39.24 38d in 237 aa.
 
 
 0.833
mntP-2
Putative membrane protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.
     
 0.785
mntP
Putative membrane protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.
     
 0.730
CBO1824
Putative Na(+)/H(+) antiporter.
  
 
 0.467
CBO2870
Hypothetical protein; No significant database matches.
       0.456
mgtE
Putative Mg2+ transporter; Acts as a magnesium transporter.
     
 0.454
gcvP-2
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
      
 0.439
adhE
Similar to Clostridium acetobutylicum aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase [acetylating] (EC 1.2.1.10) (acdh); pyruvate-formate-lyase deactivase (pfl deactivase)] AdhE or Aad or cap0162 SWALL:ADHE_CLOAB (SWALL:P33744) (862 aa) fasta scores: E(): 2.6e-212,65.04 38d in 861 aa, and to Escherichia coli, and Escherichia coli O157:H7 aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase [acetylating] (EC 1.2.1.10) (acdh); pyruvate-formate-lyase deactivase (pfl deactivase)] AdhE or Ana or b1241 or z20 [...]
   
 0.436
queE
Putative radical SAM-superfamily protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
      
 0.410
queC
Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
      
 0.410
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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