pbuX-2 protein (Clostridium botulinum A ATCC 3502)

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Score

pbuX-2

Xanthine permease. (468 aa)

Predicted Functional Partners:

xpt-2

0.869

xpt

0.859

hydA

0.847

guaA

0.785

dpaL

0.765

guaB

0.760

purL

0.708

purR

0.692

pdp

0.687

pyrB

0.657

Your Current Organism:

Clostridium botulinum A ATCC 3502

NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dpaL	guaA	CBO2888	CBO3295	Diaminopropionate ammonia-lyase.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.403
dpaL	hydA	CBO2888	CBO2886	Diaminopropionate ammonia-lyase.	D-hydantoinase.	0.848
dpaL	pbuX-2	CBO2888	CBO2887	Diaminopropionate ammonia-lyase.	Xanthine permease.	0.765
guaA	dpaL	CBO3295	CBO2888	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Diaminopropionate ammonia-lyase.	0.403
guaA	guaB	CBO3295	CBO3296	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA	hydA	CBO3295	CBO2886	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	D-hydantoinase.	0.471
guaA	pbuX-2	CBO3295	CBO2887	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Xanthine permease.	0.785
guaA	pdp	CBO3295	CBO1863	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Pyrimidine-nucleoside phosphorylase.	0.557
guaA	purL	CBO3295	CBO2580	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Formylglycinamidine ribonucleotide synthetase.	0.988
guaA	purR	CBO3295	CBO3547	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Pur operon repressor.	0.742
guaA	pyrB	CBO3295	CBO3241	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.741
guaA	xpt	CBO3295	CBO0317	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.982
guaA	xpt-2	CBO3295	CBO1139	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.982
guaB	guaA	CBO3296	CBO3295	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.999
guaB	pbuX-2	CBO3296	CBO2887	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Xanthine permease.	0.760
guaB	pdp	CBO3296	CBO1863	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Pyrimidine-nucleoside phosphorylase.	0.547
guaB	purL	CBO3296	CBO2580	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Formylglycinamidine ribonucleotide synthetase.	0.903
guaB	pyrB	CBO3296	CBO3241	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.662
guaB	xpt	CBO3296	CBO0317	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.958
guaB	xpt-2	CBO3296	CBO1139	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.958