Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CBO2929Putative exported protein. (320 aa)    
Predicted Functional Partners:
CBO3389
Putative membrane protein (pseudogene); 7 probable transmembrane helices predicted for CBO3388 by TMHMM2.0 at aa 4-18, 39-61, 66-88, 93-115,125-147, 168-190 and 212-234; Belongs to the peptidase S41A family.
  
 
 0.654
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
    0.464
CBO3541
Probable serine protease.
  
 
 0.451
CBO0428
Similar to Clostridium tetani hypothetical protein ctc01031 SWALL:Q896H3 (EMBL:AE015939) (222 aa) fasta scores: E(): 1.8e-19, 37.44 38d in 211 aa.
   
 
 0.425
CBO1138
Conserved hypothetical protein.
   
 
 0.425
CBO1298
Putative cell wall anchored protein.
   
 
 0.425
CBO1983
Conserved hypothetical protein.
   
 
 0.425
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
    0.425
CBO3436
TPR-repeat-containing protein.
   
 
 0.425
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
    0.416
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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