Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBO2969Putative competence protein. (595 aa)    
Predicted Functional Partners:
CBO0171
Putative phosphoribosyl transferase; Similar to Haemophilus influenzae competence protein F ComF or hi0434 SWALL:COMF_HAEIN (SWALL:P31773) (229 aa) fasta scores: E(): 4.7e-05, 25.83 38d in 209 aa,and to Clostridium acetobutylicum predicted amidophosphoribosyltransferase, ComC b.suntilis ortholog cac2852 SWALL:Q97F89 (EMBL:AE007783) (226 aa) fasta scores: E(): 6.3e-31, 46.63 38d in 208 aa.
 
  
 0.882
holA
Conserved hypothetical protein.
 
   
 0.840
dprA
SMF family protein; C-terminus is similar to the C-terminal region of Haemophilus influenzae Smf protein HI0985 SWALL:SMF_HAEIN (SWALL:P43862) (373 aa) fasta scores: E(): 3e-26, 35.64 id in 317 aa, and to Clostridium tetani Smf protein,putative DNA processing chain A CTC01258 SWALL:Q895L5 (EMBL:AE015940) (361 aa) fasta scores: E(): 1.5e-65,54.69 38d in 362 aa.
 
  
 0.837
CBO2970
Conserved hypothetical protein.
       0.785
secY
Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
 
   
 0.740
CBO2439
Putative magnesium chelatase.
 
  
 0.683
CBO2978
Putative competence protein.
  
  
 0.658
CBO1908
General secretion pathway protein.
   
  
 0.657
CBO2971
Putative calcium-transporting ATPase.
  
    0.638
CBO0170
Similar to Clostridium tetani conserved protein ctc00323 SWALL:Q898W5 (EMBL:AE015937) (354 aa) fasta scores: E(): 9.6e-44, 38.26 38d in 345 aa.
  
  
 0.632
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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