STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tRNA-2Conserved hypothetical protein (pseudogene); Cove score 56.86. (181 aa)    
Predicted Functional Partners:
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
    0.890
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.853
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
       0.822
modA-2
Molybdenum ABC transporter, substrate-binding lipoprotein.
  
   
 0.662
fliY
Flagellar motor switch protein FliY.
  
  
 0.639
flgL
Flagellar hook-associated protein 3.
  
 
 0.631
fliI
Flagellum-specific ATP synthase.
  
  
 0.629
fliD
Flagellar hook-associated protein; C-terminal region is similar to Bacillus halodurans flagellar hook-associated protein 2 FliD or BH3614 SWALL:FLID_BACHD (SWALL:Q9K6W0) (532 aa) fasta scores: E(): 2.1e-14, 27.55 38d in 508 aa. Full length CDS is similar to Clostridium acetobutylicum flagellar hook-associated protein CAC2205 SWALL:Q97H10 (EMBL:AE007721) (638 aa) fasta scores: E(): 1e-23, 27.36 id in 826 aa.
  
  
 0.621
mltG
Putative aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
   
  
 0.615
CBO2498
Conserved hypothetical protein.
   
    0.614
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.