Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
scfAHypothetical protein; No significant database matches. (45 aa)    
Predicted Functional Partners:
CBO3064
Putative radical SAM protein; Partially similar to Escherichia coli putative arylsulfatase regulatory protein AslB or AtsB or b3800 SWALL:ASLB_ECOLI (SWALL:P25550) (411 aa) fasta scores: E(): 0.02, 24.22 38d in 355 aa.
 
 
   0.965
ctpM
Putative arylsulfatase regulatory protein.
 
 
   0.802
trmU1
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
      
 0.681
trmU2
tRNA(5-methylaminomethyl-2-thiouridylate)- methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
      
 0.681
tilS
Conserved hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
      
 0.681
CBO3066
Putative membrane protein.
       0.653
yajC
Putative protein translocase subunit.
 
     0.630
hypA
Similar to Bradyrhizobium japonicum hydrogenase nickel incorporation protein HypA or bll6932 SWALL:HYPA_BRAJA (SWALL:Q45256) (113 aa) fasta scores: E(): 6.6e-08, 30 38d in 110 aa.
      
 0.595
hypA-2
Putative hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
      
 0.595
hemZ
Putative oxidase; Partly similar to Escherichia coli oxygen-independent coproporphyrinogen III oxidase HemN or b3867 SWALL:HEMN_ECOLI (SWALL:P32131) (457 aa) fasta scores: E(): 4.5e-11, 24.08 38d in 328 aa.
 
     0.520
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.