Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO3075Conserved hypothetical protein. (220 aa)    
Predicted Functional Partners:
efp
Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
 0.954
CBO3074
Conserved hypothetical protein.
       0.804
CBO3381
Putative membrane protein.
 
    0.737
CBO3113
Putative capsular polysaccharide biosynthesis TPR repeats containing protein.
 
    0.689
CBO3073
Conserved hypothetical protein.
       0.591
CBO3076
GntR-family transcritional regulator.
       0.584
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
    0.571
CBO0496
Hypothetical protein; No significant database matches.
  
     0.521
CBO0082
Similar to Clostridium tetani conserved protein ctc00249 SWALL:Q899D4 (EMBL:AE015936) (438 aa) fasta scores: E(): 3.8e-27, 45.7 38d in 431 aa, and to Clostridium acetobutylicum hypothetical protein Cac2985 SWALL:Q97EX1 (EMBL:AE007795) (491 aa) fasta scores: E(): 5.8e-27, 40.65 38d in 487 aa.
  
     0.515
buk1
Butyrate kinase 1; Also similar to CBO3428 (57.670 38d. in 352 aa overlap); Belongs to the acetokinase family.
   
    0.478
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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