Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBO3176Putative zinc-binding protease; Belongs to the peptidase M16 family. (409 aa)    
Predicted Functional Partners:
hymB
Putative electron-transferring subunit of iron-only hydrogenase.
  
 0.976
CBO1505
Putative oxidoreductase.
   
 0.914
recX
Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family.
 
    0.911
atpA-2
ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
   
 0.843
atpH
ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
 0.837
CBO0482
Similar to Bacillus halodurans hypothetical protein Bh1562 SWALL:Q9KCK9 (EMBL:AP001512) (268 aa) fasta scores: E(): 4.7e-46, 45.14 38d in 268 aa.
    
 0.786
CBO3174
Conserved integral membrane protein.
       0.761
CBO3367
Conserved hypothetical protein.
   
 
 0.748
atpG
ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
   
 0.740
CBO1829
Conserved hypothetical protein; Similar to the C-terminal region of several oxidoreductases such as Eubacterium acidaminophilum HymA protein.
   
 
 0.677
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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