Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBO3181Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (92 aa)    
Predicted Functional Partners:
pdp
Pyrimidine-nucleoside phosphorylase.
     
 0.912
pyrR
Putative pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
     
 0.905
pyrR-2
Pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
     
 0.905
add
Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
     
 0.904
CBO0196
Putative kinase; Similar to Clostridium tetani uridine kinase ctc00344 SWALL:Q898U6 (EMBL:AE015937) (552 aa) fasta scores: E(): 6.7e-122, 61.05 38d in 552 aa, and to Clostridium acetobutylicum fision threonyl-trna synthetase cac0672 SWALL:Q97L90 (EMBL:AE007582) (553 aa) fasta scores: E(): 4.3e-123, 61.84 38d in 553 aa.
     
 0.901
udk
Uridine kinase.
     
 0.901
CBO2819
Putative iron-sulfur oxidoreductase.
   
 
  0.901
tdK
Thymidine kinase; Similar to Rhodothermus sp. thymidine kinase Tdk SWALL:KITH_RHOSI (SWALL:Q9ZIG2) (213 aa) fasta scores: E(): 2.6e-34, 53.26 38d in 184 aa, and to Clostridium acetobutylicum thymidine kinase cac2887 SWALL:Q97F65 (EMBL:AE007786) (195 aa) fasta scores: E(): 5.1e-56,77.48 38d in 191 aa.
     
  0.900
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
     
  0.900
surE
Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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