Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
crt3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)    
Predicted Functional Partners:
thl
acetyl-CoA acetyltransferase (thiolase); Belongs to the thiolase-like superfamily. Thiolase family.
 0.999
hbd
3-hydroxybutyryl-CoA dehydrogenase.
 0.999
bcd
butyryl-CoA dehydrogenase.
 
 0.998
acdB
acyl-CoA dehydrogenase, short-chain specific.
 
 0.969
CBO2843
acyl-CoA dehydrogenase.
 
 0.969
acdA
Putative acyl-CoA dehydrogenase.
 
 0.957
CBO0418
Putative aconitase; Similar to Clostridium acetobutylicum aconitase a cac0971 SWALL:Q97KE8 (EMBL:AE007613) (642 aa) fasta scores: E(): 4e-183, 76.01 38d in 642 aa.
   
 0.849
rpsB
30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
   
 0.833
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.817
rpmG
50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
    
 
 0.809
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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