STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO3233Putative endonuclease. (261 aa)    
Predicted Functional Partners:
CBO3234
Putative secreted protein.
       0.636
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
       0.590
CBO0170
Similar to Clostridium tetani conserved protein ctc00323 SWALL:Q898W5 (EMBL:AE015937) (354 aa) fasta scores: E(): 9.6e-44, 38.26 38d in 345 aa.
  
     0.570
CBO1805
Putative acetyltransferase.
  
     0.504
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
       0.485
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
       0.473
CBO3221
Putative ABC transporter periplasmic binding protein.
 
  
 0.442
CBO0005
Similar to Clostridium perfringens hypothetical protein Cpe0005 SWALL:Q8XPF8 (EMBL:AP003185) (86 aa) fasta scores: E(): 3.2e-26, 84.7 38d in 85 aa, and to Clostridium acetobutylicum orfx SWALL:P94603 (EMBL:U35453) (87 aa) fasta scores: E(): 2.5e-25, 82.55 38d in 86 aa.
  
     0.437
CBO0405
Putative transcriptional regulator; Similar to Bacillus thuringiensis transcriptional activator NprR nprR SWALL:Q9AQ53 (EMBL:AF220563) (425 aa) fasta scores: E(): 0.00056, 21.33 38d in 436 aa, and to Bacillus subtilis response regulator aspartate phosphatase B RapB or SpoOP or bsu36690 SWALL:RAPB_BACSU (SWALL:P70962) (377 aa) fasta scores: E(): 0.014, 20.15 id in 377 aa.
  
     0.436
CBO0695
Conserved hypothetical protein.
  
     0.417
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (18%) [HD]