Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBO32452-hydroxyacyl-CoA dehydratase beta-subunit; Also similar to CBO2197 (24.4 38d), CBO2202 (29.2 id), CBO3246 (37.9), CBO3289 (26.1 38d), CBO3629 (38.9 id). (382 aa)    
Predicted Functional Partners:
CBO3242
Activator of 2-hydroxyacyl-CoA dehydratase.
 
 0.879
fldI
R-phenyllactate dehydratase activator.
 
 0.771
hadI
Activator of 2-hydroxyisocaproyl-CoA dehydratase.
 
 0.763
CBO3246
Conserved hypothetical protein.
 
    0.689
CBO1553
Putative activator of 2-hydroxyacyl-CoA dehydratase.
 
 
 0.654
CBO2574
Conserved hypothetical protein; Belongs to the sulfur carrier protein TusA family.
 
    0.587
CBO3244
2-hydroxyacyl-CoA dehydratase beta-subunit; Also similar to CBO2197 (24.4 38d), CBO2202 (29.2 id), CBO3245 (37.9), CBO3289 (26.1 38d), CBO3629 (38.9 id).
 
    
0.566
CBO2201
Putative 2-hydroxyacyl-CoA dehydratase,D-component.
 
 
 
 0.562
CBO2202
Putative bifunctional protein [includes; Similar over its N-terminal region to small subunits of 2-hydroxyacyl-CoA dehydratases (hadC, HgdB and FldC), and over its C-terminal region to activators of 2-hydroxyacyl-CoA dehydratases (HadI, hgdC and FldI). Possible bifunctional fusion protein.
 
 
0.523
fldB
R-phenyllactate dehydratase medium subunit.
 
 
 
 0.519
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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