STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO3285Conserved membrane protein. (392 aa)    
Predicted Functional Partners:
fldB
R-phenyllactate dehydratase medium subunit.
 
     0.807
fldA
E-cinnamoyl-CoA:R-phenyllactate CoA transferase large subunit; Belongs to the CoA-transferase III family.
 
     0.779
fldC
R-phenyllactate dehydratase small subunit.
 
     0.772
hadB
Subunit of oxygen-sensitive 2-hydroxyisocaproyl-CoA dehydratase; Similar to Acidaminococcus fermentans (R)-2-hydroxyglutaryl-CoA dehydratase alpha-subunit HgdA SWALL:HGDA_ACIFE (SWALL:P11569) (476 aa) fasta scores: E(): 1e-53, 39.91 38d in 471 aa. CDS contains internal deletion in comparison to the A. fermentans protein. Full length CDS is similar to Clostridium sporogenes r-phenyllactate dehydratase medium subunit FldB SWALL:Q93AL9 (EMBL:AF420489) (407 aa) fasta scores: E(): 1.7e-84, 51.47 38d in 408 aa.
 
     0.748
hadC
Subunit of oxygen-sensitive 2-hydroxyisocaproyl-CoA dehydratase.
 
     0.719
hadA
isocaprenoyl-CoA:2-hydroxyisocaproate CoA-transferase; This gene from C. difficile was cloned,overexpressed in E. coli, and characterized as 2-hydroxyisocaproate CoA-transferase, a class III enzyme (Kim et al. 2004. FEMS Microbiol. Rev. 28, 455-468); Belongs to the CoA-transferase III family.
 
     0.700
fldI
R-phenyllactate dehydratase activator.
 
     0.542
CBO1006
Conserved hypothetical protein.
  
     0.456
etfA2
Electron transfer flavoprotein alpha-subunit; N-terminal extension relative to homologues.
       0.452
etfB2
Electron transfer flavoprotein beta-subunit.
       0.433
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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