Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fldCR-phenyllactate dehydratase small subunit. (374 aa)    
Predicted Functional Partners:
fldI
R-phenyllactate dehydratase activator.
 
 
 0.972
fldB
R-phenyllactate dehydratase medium subunit.
 
 
 
 0.968
fldA
E-cinnamoyl-CoA:R-phenyllactate CoA transferase large subunit; Belongs to the CoA-transferase III family.
 
   
 0.956
hadB
Subunit of oxygen-sensitive 2-hydroxyisocaproyl-CoA dehydratase; Similar to Acidaminococcus fermentans (R)-2-hydroxyglutaryl-CoA dehydratase alpha-subunit HgdA SWALL:HGDA_ACIFE (SWALL:P11569) (476 aa) fasta scores: E(): 1e-53, 39.91 38d in 471 aa. CDS contains internal deletion in comparison to the A. fermentans protein. Full length CDS is similar to Clostridium sporogenes r-phenyllactate dehydratase medium subunit FldB SWALL:Q93AL9 (EMBL:AF420489) (407 aa) fasta scores: E(): 1.7e-84, 51.47 38d in 408 aa.
 
 
 
 0.869
hadI
Activator of 2-hydroxyisocaproyl-CoA dehydratase.
 
 
 0.847
CBO2202
Putative bifunctional protein [includes; Similar over its N-terminal region to small subunits of 2-hydroxyacyl-CoA dehydratases (hadC, HgdB and FldC), and over its C-terminal region to activators of 2-hydroxyacyl-CoA dehydratases (HadI, hgdC and FldI). Possible bifunctional fusion protein.
 
 
 0.831
CBO3242
Activator of 2-hydroxyacyl-CoA dehydratase.
 
 
 0.823
acdA
Putative acyl-CoA dehydrogenase.
 
   
 0.823
CBO3285
Conserved membrane protein.
 
     0.772
fldL
Putative CoA-ligase.
     
 0.706
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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